Leiden Sie unter chronisch spontaner Urticaria auch als Nesselsucht bekannt?
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Die Krankheit hat folgende Symptome:
Plötzlich auftretende, erhabene Hautveränderungen (Quaddeln) an Armen, Beinen, Rumpf oder Gesicht
Intensiver Juckreiz, häufig begleitet von Brennen
Schwellungen (Angioödeme) insbesondere an Lippen, Augenlidern, Händen oder Füßen
Hautveränderungen, die oft innerhalb von Stunden verschwinden, aber an anderer Stelle neu auftreten
Beschwerden, die über Wochen und Monate bestehen können (chronische Urtikaria), immer wiederkehren und zu hoher Belastung führen
Die Ursachen der Urtikaria sind vielfältig.
Bei der akuten Form handelt es sich häufig um allergische Reaktionen oder externe Auslöser wie bestimmte Lebensmittel, Medikamente oder Infekte.
Bei der chronischen Urtikaria (hier für suchen wir Studienteilnehmer), die länger als sechs Wochen anhält, lässt sich dagegen oft kein eindeutiger Auslöser feststellen – man spricht dann von einer spontanen Urtikaria. Dennoch können auch bei der chronischen Form Faktoren wie Medikamente, Stress, Infektionen oder Autoimmunreaktionen eine Rolle spielen.
Auf körperlicher Ebene sind vor allem Immunzellen, insbesondere Mastzellen, beteiligt:
Sie setzen Botenstoffe wie Histamin frei, die die Blutgefäße erweitern und dadurch die typischen Quaddeln und Schwellungen verursachen.
Wir führen eine klinische Studie in unserem Studienzentrum in Mainz durch.
Sie wollen wissen, ob Sie dafür in Frage kommen?
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